1. Develop a roadmap for research and practice of ethics of genomic research in Africa. Africa is on the threshold of the genomics revolution with emerging plans to increase training and research capacity in African genomics. This needs urgent proposals to develop an ethical training and research framework for gene-ethics in Africa.
Ethics and Genomics Research in Africa (EAGER-AFRICA) Conference 2011 has come and gone but the impact will stay with us always. The website afford us the oppotunity of reliving the incredible time we had together through pictures and video, you can also download workshop slides online.
Study shows that gene signature identifies high-risk patients with early-stage NSCLC
Researchers have shown that testing for a specific collection of genes in early-stage non-small-cell lung cancer (NSCLC) tissue accurately predicts prognosis. The 15-gene signature appears to have promising potential to identify patients with NSCLC who may or may not benefit from adjuvant chemotherapy.
Flipping a gene switch reactivates fetal hemoglobin, may reverse sickle cell disease
Hematology researchers at The Children's Hospital of Philadelphia have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period. Because this fetal hemoglobin is unaffected by the genetic defect in sickle cell disease (SCD), the cell culture findings may open the door to a new therapy for the debilitating blood disorder.
Finding that single microRNA powers motor activity has implications for treating severe treatment-refractory epilepsy
New research from the Icahn School of Medicine at Mount Sinai shows that microRNA-128 is one of the strongest regulators of nerve cell excitability and motor activity, and that it does so by adjusting an entire neuronal signaling pathway.
Mindfulness meditation affects gene expression
With evidence growing that meditation can have beneficial health effects, scientists have sought to understand how these practices physically affect the body.A new study by researchers in Wisconsin, Spain, and France reports the first evidence of specific molecular changes in the body following a period of mindfulness meditation.
PKM2 controls mitosis, saving cancer cells from death and promoting brain tumor growth
Researchers have caught a protein they previously implicated in a variety of cancer-promoting roles performing a vital function in cell division, survival and development of brain tumors.In a paper published in Molecular Cell, Zhimin Lu, Ph.D.
Third-generation gene sequencing available to all in the future
DNA sequencing seems to be an eternal theme for human due to the desire of ascertaining the nature of life. Professor QIAN Linmao and his group from Tribology Research Institute, Southwest Jiaotong University were working on the optimization of the third-generation sequencing technique based on nanopore.
The Human Heredity and Health in Africa (H3Africa) Initiative aims to facilitate a contemporary research approach to the study of genomics and environmental determinants of common diseases with the goal of improving the health of African populations. To accomplish this, the H3Africa Initiative aims to create and support the development of the necessary expertise among African scientists, and to establish networks of African investigators. It is envisaged that studies performed in the H3Africa Initiative will inform subsequent strategies to address more broadly health inequities in both communicable and non-communicable diseases eventually leading to health benefits in Africa.