1. Develop a roadmap for research and practice of ethics of genomic research in Africa. Africa is on the threshold of the genomics revolution with emerging plans to increase training and research capacity in African genomics. This needs urgent proposals to develop an ethical training and research framework for gene-ethics in Africa.
Ethics and Genomics Research in Africa (EAGER-AFRICA) Conference 2011 has come and gone but the impact will stay with us always. The website afford us the oppotunity of reliving the incredible time we had together through pictures and video, you can also download workshop slides online.
Genetic cause found for premature ovarian failure
The results, published in The New England Journal of Medicine and Human and Molecular Genetics journals, demonstrate for the first time that mutation in STAG3 gene is the major cause of human fertility disorders as it provokes a loss of function of the protein it encodes.
Testis size matters for genome evolution
In many primates, females mate with multiple partners, causing an often-intense competition amongst males to pass along their DNA to be king of the genome as well as the jungle.
Darwin: It's not all sexual (selection)
Since the days of Darwin, scientists have considered bird song to be an exclusively male trait, resulting from sexual selection. Now a team of researchers from the University of Maryland, Baltimore County (UMBC), the University of Melbourne in Australia, Leiden University in the Netherlands and The Australian National University says that's not the whole story.
Researchers capture 'most complete' picture of gene expression in cancer cell cycle
Uncontrolled cell growth and division is a hallmark of cancer. Now a research project led by the University of Dundee has provided the most complete description to date of the gene activity which takes place as human cells divide.
Sudden cardiac death: genetic disease ARVC more common than hitherto assumed
Scientists have thrown light on the genetic mutation that causes a particularly severe genetic disease (ARVC5) on the Canadian island Newfoundland in 2008. At first, they assumed that it was a genetic anomaly limited to this Canadian province. In 2010, Milting's team - and at the same time a team of researchers from Copenhagen - proved that the "Newfoundland mutation" did also occur in Europe.
3-D changes in DNA may lead to a genetic form of Lou Gehrig's disease
New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die.
The Human Heredity and Health in Africa (H3Africa) Initiative aims to facilitate a contemporary research approach to the study of genomics and environmental determinants of common diseases with the goal of improving the health of African populations. To accomplish this, the H3Africa Initiative aims to create and support the development of the necessary expertise among African scientists, and to establish networks of African investigators. It is envisaged that studies performed in the H3Africa Initiative will inform subsequent strategies to address more broadly health inequities in both communicable and non-communicable diseases eventually leading to health benefits in Africa.