1. Develop a roadmap for research and practice of ethics of genomic research in Africa. Africa is on the threshold of the genomics revolution with emerging plans to increase training and research capacity in African genomics. This needs urgent proposals to develop an ethical training and research framework for gene-ethics in Africa.
Ethics and Genomics Research in Africa (EAGER-AFRICA) Conference 2011 has come and gone but the impact will stay with us always. The website afford us the oppotunity of reliving the incredible time we had together through pictures and video, you can also download workshop slides online.
Studies uncover new insights into pathophysiology of sickle cell disease and thalassemia, may help improve standard of care
New research presented during the 55th American Society of Hematology Annual Meeting and Exposition in New Orleans uncovers several important insights into the pathophysiology of sickle cell disease and thalassemia that may soon translate into the development of better, more targeted treatments for hundreds of thousands of patients worldwide.
FoundationOne™ Heme enables identification of genomic alterations not identified by conventional methods across hematologic malignancies
Foundation Medicine has announced new data demonstrating that its fully informative genomic profile for hematologic cancers, FoundationOne™ Heme, can be performed in routine clinical cancer specimens to identify all classes of genomic alterations, including gene fusions, across hundreds of genes related to oncogenesis in patients with hematologic malignancies.
Identification of 10-gene biomarker has implications for ovarian cancer discovery, survival outcomes
Researchers in the Women's Cancer Program at Cedars-Sinai's Samuel Oschin Comprehensive Cancer Institute have identified a series of 10 genes that may signify a trifecta of benefits for women diagnosed with ovarian cancer and ultimately reflect improved survival outcomes.
We each live in a unique odor world
According to Gertrude Stein, "A rose is a rose is a rose," but new research indicates that might not be the case when it comes to the rose's scent. Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals.
Gene discovered that plays a part in one per cent of all cancers
Researchers have identified a gene that drives the development of tumours in over one per cent of all cancer patients. This is the first time that the gene CUX1 has been broadly linked to cancer development.The team discovered that, when CUX1 is deactivated, a biological pathway is activated that increases tumour growth.
Discovery of CXCR4 mutations in Waldenstrom's Macroglobulinemia helps identify which patients are more likely to benefit from ibrutinib
In nearly one-third of patients with Waldenstrom's Macroglobulinemia, a specific genetic mutation switches on the disease, and a new drug that blocks the defective gene can arrest the disease in animal models, researchers at Dana-Farber Cancer Institute and allied institutions reported at the 2013 annual meeting of the American Society of Hematology (ASH).
The Human Heredity and Health in Africa (H3Africa) Initiative aims to facilitate a contemporary research approach to the study of genomics and environmental determinants of common diseases with the goal of improving the health of African populations. To accomplish this, the H3Africa Initiative aims to create and support the development of the necessary expertise among African scientists, and to establish networks of African investigators. It is envisaged that studies performed in the H3Africa Initiative will inform subsequent strategies to address more broadly health inequities in both communicable and non-communicable diseases eventually leading to health benefits in Africa.